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July 2009

Anti–Double-Stranded DNA–Positive Unilateral Generalized Morphea in an Adult, Possibly Exacerbated by Ibuprofen

Arch Dermatol. 2009;145(7):844-846. doi:10.1001/archdermatol.2009.131

A 20-year-old healthy Jewish woman of Yemenite origin presented with a 2-year history of a linear eruption on the right shoulder and thorax, upper and lower arm, dorsal surface of the hand, and lower leg. She also had an atrophic furrow on the right side of her forehead consisting of erythematous, conflating macules that later became ivory-white, shiny, indurated, and occasionally itchy (Figure 1). The lesions were distributed along Blaschko lines (Figure 2).1 Her 27-year-old sister was diagnosed as having systemic lupus erythematosus (SLE) at age 12 years.

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