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September 2009

Linear Pruritic Eruption With Onychodystrophy in a 1-Year-Old Girl—Diagnosis

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Copyright 2009 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2009

Arch Dermatol. 2009;145(9):1053-1058. doi:10.1001/archdermatol.2009.185-b

Histologic sections of the hematoxylin-eosin–stained biopsy specimen showed an acanthotic epidermis with overlying orthokeratosis and parakeratosis. A dense lichenoid infiltrate was associated with epidermal basal vacuolar changes and scattered apoptotic keratinocytes. There was also a superficial and deep perivascular and perieccrine lymphohistiocytic infiltrate. A periodic acid–Schiff stain failed to reveal fungal organisms. The combined histologic findings and clinical appearance was that of lichen striatus.

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