Dermoscopy and Confocal Microscopy of Nested Melanoma of the Elderly: Recognizing a Newly Defined Entity | Dermatology | JAMA Dermatology | JAMA Network
[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 34.234.207.100. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Case Report/Case Series
August 2013

Dermoscopy and Confocal Microscopy of Nested Melanoma of the Elderly: Recognizing a Newly Defined Entity

Author Affiliations
  • 1Units of Dermatology and Skin Cancer, Arcispedale Santa Maria Nuova, Istituto di Ricovero e Cura a Carattere Scientifico, Reggio Emilia, Italy
  • 2Department of Dermatology, Medical University of Graz, Graz, Austria
  • 3Pathology, Arcispedale Santa Maria Nuova, Istituto di Ricovero e Cura a Carattere Scientifico, Reggio Emilia, Italy
  • 4Department of Dermatology, University of Modena and Reggio Emilia, Italy
JAMA Dermatol. 2013;149(8):941-945. doi:10.1001/jamadermatol.2013.321
Abstract

Importance  Nested melanoma of the elderly is a newly identified histopathologic variant of superficial spreading melanoma, characterized by intraepidermal large nests. However, the clinical, dermoscopic, and confocal aspects have been depicted only partially.

Observations  In our cases series, nested melanoma was a flat, irregularly shaped lesion with variably pigmented and irregularly distributed globules on dermoscopic examination. Confocal microscopy revealed the presence of a “clod” pattern made of large compact nests with variable atypia. These findings correlated well with histopathologic features.

Conclusions and Relevance  Nested melanoma of the elderly should be included in the differential diagnosis when a flat pigmented lesion, showing dermoscopically an irregular globular pattern, is seen in a patient older than 60 years.

×