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The Cutting Edge
August 1998

Successful Treatment of Intractable Palmoplantar Pruritus With Ondansetron

Author Affiliations


Arch Dermatol. 1998;134(8):925-926. doi:10.1001/archderm.134.8.925

A 61-year-old woman presented with a 2-year history of intense itching of her palms and soles. The irritation was relieved only by plunging her hands and feet into cold water. She would awaken at least 4 times per night to rub her hands and feet for 15 minutes before falling asleep again. Her symptoms were more marked in the summer compared with the winter. Her medical history included chronic obstructive pulmonary disease, hiatal hernia, nasal polyps, and 3 previous deep vein thrombi. She took sulfalene tablets and ipratropium bromide, albuterol, and beclomethasone dipropionate aerosol inhalers during the winter for her bronchitis.