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THE fluoroquinolones ciprofloxacin and ofloxacin are among the antimicrobials recommended for treating uncomplicated gonorrhea.1 Fluoroquinolone-resistant strains of Neisseria gonorrhoeae have been identified frequently during the 1990s in the Far East.2 In the United States, fluoroquinolone-resistant N gonorrhoeae has been reported sporadically; resistance associated with clinical treatment failure has been reported previously in only one person, who probably acquired the infection in the Philippines.3-5 This report describes the results of an investigation in 1997 of two cases of gonococcal infection in the United States with strains with a higher level of fluoroquinolone resistance than reported previously; clinical treatment failure occurred in one case.
Fluoroquinolone-Resistant Neisseria gonorrhoeae—San Diego, California, 1997. Arch Dermatol. 1998;134(8):1049–1050. doi:https://doi.org/10.1001/archderm.134.8.1049
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