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In This Issue of JAMA Dermatology
December 2018


JAMA Dermatol. 2018;154(12):1371. doi:10.1001/jamadermatol.2017.3868

In this cohort study of participants in the Nurses’ Health Study II, Li et al identified 4945 incident cases of rosacea and found a significant inverse association between risk of rosacea and increased caffeine intake, particularly from coffee. This association was not found for caffeine from other food sources (eg, tea, soda, chocolate). These findings do not support limiting caffeine intake to prevent rosacea and may have implications for the causes of and clinical approach to rosacea. Wehner and Linos provide an Editorial.


In this multicenter cohort of 467 moderately dysplastic nevi with positive histologic margins, Kim et al found no cases of cutaneous melanoma at the biopsy site after nearly 7 years’ follow-up. However, 2 or more biopsied dysplastic nevi carried increased risk of a subsequent cutaneous melanoma at another site. Observation of moderately dysplastic nevi with positive margins may be reasonable, and screening for subsequent cutaneous melanoma at other sites seems warranted for those with multiple histologic dysplastic nevi.