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In This Issue of JAMA Dermatology
April 2019


JAMA Dermatol. 2019;155(4):409. doi:10.1001/jamadermatol.2018.3508

With the widespread use of systemic antibiotics, understanding their association with skin microbiota is important. In this pilot study of 4 women with acne, Chien et al found that oral minocycline treatment was associated with changes in the composition and diversity of skin microbiota, with variable rates of recovery across individual patients. Understanding the association between systemic antibiotic use and skin microbiota may help clinicians decrease the likelihood of skin comorbidities related to microbial dysbiosis. Scharschmidt provides an Editorial.


Continuing Medical Education

Concerns about the pediatric use of general anesthesia contributes to the difficulty of timing of laser treatment for port-wine stains (PWS) in infants. In this cohort study of 197 infants with PWS (mean age, 3.4 months), Jeon et al found that pulsed dye laser treatment of PWS without anesthesia was followed by 99% clearance in more than three-quarters of cases with no scarring or permanent pigmentary change. These findings suggest that pulsed dye laser may be a safe and effective treatment of PWS in infancy. Mathes and Frieden provide an Editorial.