Customize your JAMA Network experience by selecting one or more topics from the list below.
Garden JM, O'Banion MK, Bakus AD, Olson C. Viral Disease Transmitted by Laser-Generated Plume (Aerosol). Arch Dermatol. 2002;138(10):1303–1307. doi:10.1001/archderm.138.10.1303
To evaluate the possibility of disease transmission through liberated plume from virally infected tissue that is exposed to the carbon dioxide laser.
Bovine papillomavirus–induced cutaneous fibropapillomas were exposed to the carbon dioxide laser. Laser settings were within the range of clinically used settings. The laser plume (aerosol) was suctioned and collected and then reinoculated onto the skin of calves.
University laboratory research center.
Main Outcome Measures
Laser plume viral content and postinoculation tumor growth were analyzed and documented.
Collected laser plume contained papillomavirus DNA in all tested laser settings. The viral DNA was most likely encapsulated. Tumors developed at laser plume–inoculated sites for all laser parameter settings. Histological and biochemical analyses revealed that these tumors were infected with the same virus type as present in the laser plume.
Laser plume has been shown, for the first time to our knowledge, to actually transmit disease. Strict care must be maintained by the laser practitioner to minimize potential health risks, especially when treating viral-induced lesions or patients with viral disease.
Create a personal account or sign in to: