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Oral lichen planus is an uncommon, difficult-to-treat, chronic inflammatory disorder characterized by painful white striations, papules, and plaques on the buccal, lingual, and gingival mucosa. Current therapeutic options include topical, intralesional, or systemic corticosteroids; topical anesthetics; topical or systemic retinoids; and topical immunomodulators. Narrowband UV-B phototherapy has been used successfully for cutaneous lichen planus, but no delivery system exists for intraoral exposures. In this open-label pilot study, Trehan and Taylor demonstrate the effective use of a flexible fiberoptic delivery system for the 308-nm excimer laser treatment of oral lichen planus.
Psoriasis is one of the most common conditions seen in dermatological practice, and it has profound negative effects on patients' quality of life. The psychosocial effects of psoriasis on a patient's life may be unrelated to the objective quantification of the clinical severity of disease as assessed by tools such as the Psoriasis Area Severity Index (PASI) score. Many patients are frustrated with this chronic dynamic disease and the perceived ineffectiveness of therapy. In this open prospective study, Zaghloul and Goodfield assess adherence to medical therapies by direct questioning and by identifying social, treatment-related, and disease distribution factors that affect medication compliance.
This Month in Archives of Dermatology. Arch Dermatol. 2004;140(4):395. doi:10.1001/archderm.140.4.395
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