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Article
January 1941

VITAMIN D THERAPY IN DERMATOLOGY

Author Affiliations

PHILADELPHIA

Arch Derm Syphilol. 1941;43(1):145-154. doi:10.1001/archderm.1941.01490190148011
Abstract

In 1937 there appeared in the Public Health Reports of the United States Public Health Service a preliminary report by Ceder and Zon1 on the use of massive daily doses of vitamin D in the treatment of psoriasis, and they suggested that "this is a practical, simple and effective treatment for the control of psoriasis." In the following year, Maynard2 reported on the use of large doses (20 to 80 drops daily [probably 5,000 to 14,000 U. S. P. units of vitamin D]) of viosterol in the treatment of acne vulgaris and concluded that "from the patients' viewpoint it has left little to be desired as they find themselves improving both in appearance and in general well being." These two papers were immediately widely quoted in the medical columns of the daily newspapers, with the result that there was quick demand by sufferers from psoriasis and acne for

References
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Ceder, E. T., and Zon, L.:  Treatment of Psoriasis with Massive Doses of Crystalline Vitamin D and Irradiated Ergosterol: A Preliminary Report ,  Pub. Health Rep. 52:1580, 1937.Crossref
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Maynard, M. T. R.:  Vitamin D in Acne ,  California & West. Med. 49: 127, 1938.
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Puestow, C. B.; Poncher, H. G., and Hammett, H.:  Vitamin Oils in the Treatment of Burns ,  Surg., Gynec. & Obst. 66:622, 1938.
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The preparation used was concentrated viosterol in oil (Merrell).
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Reed, C. I.; Struck. H. C., and Steck, I. E.:  Vitamin D: Chemistry, Physiology, Pharmacology, Pathology, Experimental and Clinical Investigations , Chicago. University of Chicago Press, 1939.
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MacKee, G. M., in  Symposium on the Practical Management of Acne Vulgaris ,  J. Invest. Dermat. 3:143, 1940.
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