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Article
February 1941

LEUKODERMA ACQUISITUM CENTRIFUGUM: REPORT OF A CASE IN WHICH THE CENTRAL NEVI WERE DESTROYED AND THE LEUKODERMIC HALOES THEN TREATED WITH ULTRAVIOLET RADIATION IN AN ATTEMPT TO RESTORE THE PIGMENT

Author Affiliations

NEW YORK

From the New York Hospital and from the Department of Medicine (Dermatology), Cornell University Medical College.

Arch Derm Syphilol. 1941;43(2):357-360. doi:10.1001/archderm.1941.01490200139012
Abstract

Leukoderma acquisitum centrifugum is a relatively rare condition, but several articles on this subject have appeared since Sutton1 reported his 2 cases in 1916. The literature and the various theories proposed to explain the mechanism of the production of these lesions were adequately reviewed by Feldman and Lashinsky2 in 1936, but I was unable to find any report of what effect, if any, on the surrounding leukodermic area would follow destruction of the central nevus. If, as some authors assume, the nevus drains pigment from the surrounding area, theoretically destruction of the nevus might permit the leukodermic area to regain its normal supply of pigment. An opportunity to study this question was afforded me by a patient with typical lesions of leukoderma acquisitum centrifugum who came to the clinic for removal of the pigmented nevi.

REPORT OF CASE  F. S., a white girl aged 13, was first seen

References
1.
Sutton, R. L.:  An Unusual Variety of Vitiligo (Leukoderma Centrifugum Acquisitum) ,  J. Cutan. Dis. 34:797 ( (Nov.) ) 1916.
2.
Feldman, S., and Lashinsky, I. M.:  Halo Nevus: Leukoderma Centrifugum Acquisitum (Sutton); Leukopigmentary Nevus ,  Arch. Dermat. & Syph. 34:590 ( (Oct.) ) 1936.
3.
Weber, F. P.:  A Law Regarding the Distribution of Depigmented Patches of Vitiligo, When They Are Superadded to Mole-Like Nevi ,  Brit. J. Child. Dis. 21:202 ( (July) -Sept.) 1924.
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