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In the twenty years since the publication of the paper introducing potassium permanganate as a remedy in the treatment of dermatophytosis, by myself in collaboration with the late Dr. Benjamin F. Ochs,1 the merits and shortcomings of this treatment have become more definitely established.
The greatest drawback to the use of this drug is that it is not stable and that it cannot be combined with any base in the form of either an ointment or a drying lotion. For that reason it is suitable only for a hot soak or a wet dressing, and, naturally, its use is limited to the early acute stage of the disease.
There is one period during the course of the disease when the use of irritating ointments and greases is, to say the least, inadvisable, if not contraindicated, namely, when the acuteness of the lesions has subsided, the blebs have broken and
Feldman S. ZINC PEROXIDE IN THE TREATMENT OF DERMATOPHYTOSIS. Arch Derm Syphilol. 1941;44(4):674–675. doi:10.1001/archderm.1941.01500040129013
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