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Article
March 1951

TUBERCULOSIS VERRUCOSA CUTIS TREATED WITH STREPTOMYCIN

Author Affiliations

PROVIDENCE, R. I.

From the Department of Dermatology and Syphilology of Bellevue Hospital, Dr. Frank C. Combes, chief of service, New York.

AMA Arch Derm Syphilol. 1951;63(3):378-380. doi:10.1001/archderm.1951.01570030092013
Abstract

Numerous reports have attested to the efficacy of streptomycin in the treatment of cutaneous tuberculosis.1 However, its beneficial action, for the most part, has been observed only in certain types of involvement, namely cutaneous sinuses and fistulas. A review of the literature discloses only two cases of tuberculosis verrucosa cutis treated with streptomycin. The first was included in a report by Combes, Canizares, Shatin and Kaufman,1f and the second was more recently presented by Allison, Robinson and Frutchey.2 In both cases 1 Gm. of streptomycin was given daily for six weeks with rapid involution of the lesions. This report concerns a third patient with tuberculosis verrucosa cutis successfully treated with streptomycin.

REPORT OF A CASE  M. C., a 35 year old white woman, gave a history of hoarseness and cough of several months' duration. Roentgenologic studies showed evidence of moderately advanced pulmonary tuberculosis, confirmed by the finding of tubercle bacilli in her sputum. On her left hand were several

References
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 Streptomycin in the Treatment of Infections, Committee on Chemotherapeutics and Other Agents, National Research Council ,  J. A. M. A. 132:70 ( (Sept. 14) ) 1946.Crossref
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O'Leary, P. A.; Ceder, E. T.; Hinshaw, H. C., and Feldman, W. H.::  Treatment of Various Types of Cutaneous Tuberculosis with Promizole and Streptomycin ,  Arch. Dermat. & Syph. 55:222 ( (Feb.) ) 1947.
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 Annual Report of the Committee on Therapy and the Subcommittee on Streptomycin ,  J. A. M. A. 135:641 ( (Nov. 8) ) 1947.
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Feldman, W. H., and Hinshaw, H. C.:  Streptomycin: A Valuable Anti-Tuberculosis Agent ,  Brit. M. J. 1:87 ( (Jan. 17) ) 1948.
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Combes, F. C.; Canizares, O.; Shatin, H., and Kaufman, C.:  Streptomycin in Dermatology: Its Value and Limitations ,  New York State J. Med. 48:2024 ( (Sept. 15) ) 1948.
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Whitehead, H. G.:  The Present Status of Streptomycin in the Treatment of Tuberculosis ,  Bull. School Med. Univ. Maryland 33:79 ( (Oct.) ) 1948.
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Allison, J. R.; Robinson, A. M., and Frutchey, L. D.:  Tuberculosis Verrucosa Cutis Successfully Treated with Streptomycin ,  J. Invest. Dermat. 13:207 ( (Oct.) ) 1949.
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Michelson, H. E., in discussion on Ringrose, E.:  Tuberculosis Verrucosa Cutis of the Finger ,  Arch. Dermat. & Syph. 61:516 ( (March) ) 1950.
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Pfuetze, K. H., and Pyle, M. M.:  Streptomycin in Tuberculosis ,  Minnesota Med. 31:1309 ( (Dec.) ) 1948.
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Johnson, H. M.:  Dihydrostreptomycin and Potassium Iodide in the Treatment of Tuberculosis Verrucosa Cutis ,  J. Invest. Dermat. 15:61 ( (July) ) 1950.
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