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Soft-tissue augmentation is useful in treating the aging face as well as lipodystrophy associated with highly active antiretroviral therapy. Bio-Alcamid is a cross-linked polyalkylamide gel filler that is not currently approved by the US Food and Drug Administration for use in the United States. In this case series, Chrastil-LaTowsky et al describe 2 cases of recurrent inflammatory reactions that occurred more than 1 year after injection of Bio-Alcamid gel. Although the permanent nature of Bio-Alcamid is often considered an advantage, these cases emphasize the risks associated with early- and late-occurring complications. Globalization of the cosmetic surgery market presents unique challenges to physicians, who must be aware of potential presentations and complications of products, even those not routinely used in local practice.
This Month in Archives of Dermatology. Arch Dermatol. 2009;145(11):1221. doi:10.1001/archdermatol.2009.284
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