To evaluate the efficacy and safety of a novel gel in the treatment of mycosis fungoides, Lessin and colleagues compared response rates to mechlorethamine, 0.02%, gel vs compounded ointment in 260 patients with stage IA to IIA disease. Tumor response and adverse events were assessed, as well as serum drug levels in a subset of patients.
Carter and coauthors identified factors associated with poor outcomes in perineurally invasive squamous cell carcinoma.
Schneider and colleagues calculate sunbed use prevalence rates, investigate the motivations for tanning, and identify typical target groups for interventions to prevent skin cancer.
Ozog et al assessed mature burn scars treated with a fractional carbon dioxide laser for changes in histological architecture, types I and III collagen ratios, density of elastic tissue, and subjective measures of clinical improvements.
Lloyd-Lavery et al investigate the possible association between bullous pemphigoid and multiple drugs in a retrospective case-control study in the United Kingdom.
el-Azhary and colleagues report their experience with low-dose tissue plasminogen activator in the treatment of calciphylaxis.
Armstrong et al conducted a meta-analysis of 27 observational studies to determine whether there is an association between psoriasis and diabetes mellitus.
Grimes and coauthors describe the preliminary results of 4 patients with generalized vitiligo who developed repigmentation using afamelanotide and narrowband UV-B phototherapy.
Scharschmidt et al describe an immune reconstitution reaction resulting in the unmasking of leprosy in an HIV-negative stem cell transplant recipient.
Surovy et al describe the development, treatment, and outcome of a variant of Sweet syndrome in 3 morbidly obese patients.
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