To determine the relationship between HLA-B*1502 and carbamazepine-induced Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), Tangamornsuksan performed a comprehensive database search without language restriction from inception through December 2012. The primary outcome was carbamazepine-induced SJS and TEN, given as an overall OR.
Julià et al assess the role of 2 Fcγ receptor polymorphisms in the response to anti–tumor necrosis factor therapy in psoriasis.
Drake et al evaluate the safety and efficacy of once-daily antimycobacterial therapy on the resolution of chronic cutaneous sarcoidosis lesions.
Wilcox and coauthors investigate healing outcomes and debridement frequency in a large wound data set. See Invited Comentary by Lebrun and Kirsner.
Malvehy et al describe a method for sampling fresh tissue from primary melanoma and test whether the area of maximal thickness can be identified with dermoscopy to ensure it remains available for routine histopathological diagnosis. Agreement between 2 observers on the identification of the thickest part of the melanoma was studied. See the Editorial by Soyer.
Choi et al describe a patient who developed a subacute cutaneous lupus erythematosus (SCLE)–like eruption after being administered gemcitabine and discuss 16 other published cases of chemotherapeutic drug–induced SCLE. See the Invited Commentary by Callen.
Sarin et al describe a case of agminated Spitz nevi arising in a nevus spilus and use exome sequencing to identify a clonal activating point mutation in HRAS (c.37G→C) in the Spitz nevi and underlying nevus spilus.
Sartori-Valinotti and coauthors report their experience with the clinical presentation, diagnosis, and management of otic lichen planus in 19 patients treated during a 10-year period at Mayo Clinic, Rochester, Minnesota.
Pohl et al describe a malignant melanoma that developed on a nevus within a tattoo that had undergone laser removal.
Burgdorf and Bickers continue to describe the state of dermatology in the United States and in German-speaking countries in the 1930s during the rise to power of Adolf Hitler that initiated the exodus of Jewish dermatologists to the United States.