Andrew Lee, MBBS; Jennifer Bradford, MBBS; Gayle Fischer, MD
free access
JAMA Dermatol. 2015;151(10):1061-1067. doi:10.1001/jamadermatol.2015.0643
This single-center cohort study of adult patients with vulvar lichen sclerosis suggests that individualized preventive topical corticosteroid regimens that achieve objective normality of skin color and texture combined with regular long-term follow-up visits may modify the course of the disease.
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Editorial
Reduced Risk of Squamous Cell Carcinoma With Adequate Treatment of Vulvar Lichen Sclerosus
Susan M. Cooper, MD, FRCP; Nina Madnani, MD, DVD; Lynnette Margesson, MD, FRCPC
JAMA Dermatol
Mihaela Balu, PhD; Christopher B. Zachary, MD; Ronald M. Harris, MD; et al.
free access
JAMA Dermatol. 2015;151(10):1068-1074. doi:10.1001/jamadermatol.2015.0453
This study demonstrates, in a limited patient population, that noninvasive in vivo multiphoton microscopic imaging can provide label-free contrast that reveals several characteristic features of basal cell carcinoma lesions.
Francesca Farnetani, MD; Alon Scope, MD; Ralph P. Braun, MD; et al.
free access
JAMA Dermatol. 2015;151(10):1075-1080. doi:10.1001/jamadermatol.2015.0810
This observational retrospective web-based study of a set of reflectance confocal microscopy (RCM) images collected at a tertiary academic medical center tests interobserver reproducibility of recognition of previously published RCM descriptors and accuracy of RCM-based skin cancer diagnosis.
Howard W. Rogers, MD, PhD; Martin A. Weinstock, MD, PhD; Steven R. Feldman, MD, PhD; et al.
free access
JAMA Dermatol. 2015;151(10):1081-1086. doi:10.1001/jamadermatol.2015.1187
This thorough nationwide estimate of the incidence of nonmelanoma skin cancer reports evidence of continued increases in numbers of skin cancer diagnoses and affected patients in the United States.
Neel Maria Helvind, MD; Lisbet Rosenkrantz Hölmich, MD, DMSc; Sigrun Smith, Bach San Scient Publ; et al.
free access
JAMA Dermatol. 2015;151(10):1087-1095. doi:10.1001/jamadermatol.2015.1481
This national database study of in situ and malignant melanoma in Denmark confirms an increase in melanoma incidence and the importance of secondary melanoma prevention, in particular among the population older than 60 years.
Haley B. Naik, MD, MHSc; Seth M. Steinberg, PhD; Lindsay A. Middelton, RN, CGC; et al.
free access
has audio
JAMA Dermatol. 2015;151(10):1096-1102. doi:10.1001/jamadermatol.2015.1793
This randomized clinical trial assesses the efficacy of intralesional botulinum toxin A in the management of pain associated with cutaneous leiomyomas.
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Audio Author Interview:
Botulinum Toxin A to Treat Painful Cutaneous Leiomyomas (JAMA Dermatology)
Giuliana Carlos, MBBS; Rachael Anforth, BMed; Arthur Clements, BSc (Med), MBBS; et al.
free access
JAMA Dermatol. 2015;151(10):1103-1109. doi:10.1001/jamadermatol.2015.1745
This cohort study reports that the prevalence of cutaneous toxic effects is decreased with a combination of dabrafenib and trametinib therapy compared with vemurafenib and dabrafenib monotherapy in a population with inoperable stages IIIC and IV malignant melanoma.