According to this longitudinal cohort study, it seems unlikely that topical pimecrolimus as it was used in the Pediatric Eczema Elective Registry cohort to treat atopic dermatitis is associated with an increased risk of malignancy. See the Editorial by Hanifin.
Available toxicity information from clinical trials of finasteride in men with androgenic alopecia (AGA) is very limited, is of poor quality, and seems to be systematically biased. In a cohort of men prescribed finasteride for routine treatment of AGA, most would have been excluded from the pivotal studies that supported US FDA approval for AGA. Published reports of clinical trials provide insufficient information to establish the safety profile for finasteride in the treatment of AGA.
This prospective population-based cohort study found a stable 2 to 3 times elevated risk by number of previous melanomas for patients with either familial or sporadic melanoma.
In a prospective observational cohort study of patients with plaque-type psoriasis, Menting et al establish a therapeutic range for adalimumab trough levels of 3.51 mg/L to 7.00 mg/L, which corresponds to an optimal clinical effect.
This original investigation shows that primary adherence to an acne treatment regimen is better when only 1 treatment is prescribed.
This retrospective analysis suggests that leukocyte hyperactivation may underlie cutaneous lesions in patients with PLCG2-associated antibody deficiency and immune dysregulation.
This case report describes the successful use of narrowband UV-B phototherapy for the treatment of sclerotic chronic cutaneous graft-vs-host-disease (GVHD). Further study should be performed to evaluate the effectiveness of this therapeutic modality for patients with sclerotic chronic cutaneous GVHD.
This case report shows that somatic GJB2 mutation is sufficient to cause porokeratotic eccrine ostial and dermal duct nevus.
This case describes opportunistic infection with Trichosporon inkin refractory to conventional antifungal treatment.
This case report describes a patient with treatment-resistant mucous membrane pemphigoid and persistence of IgA-secreting B cells after rituximab therapy.
This database study finds that the economic burden of psoriasis is substantial and significant in the United States.
This case of a painless leg ulcer in an immunosuppressed patient with diverticulitis, a neutropenic fever, and sepsis due to multidrug-resistant Pseudomonas aeruginosa infection showed a cutaneous ulcer with a raised erythematous border and a base with purulent debris. What is your diagnosis?
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