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May 2019 - January 1920

Decade

Year

Issue

April 2016, Vol 152, No. 4, Pages 361-495

In This Issue of JAMA Dermatology

Highlights

Abstract Full Text
free access
JAMA Dermatol. 2016;152(4):361. doi:10.1001/jamadermatol.2015.3247
Viewpoint

Should We Leave the Skin Biopsies to the Dermatologists?

Abstract Full Text
JAMA Dermatol. 2016;152(4):371-372. doi:10.1001/jamadermatol.2015.5051

This Viewpoint describes dermatologists’ accuracy at skin cancer diagnosis compared with other health care professionals and hypothesizes that prioritizing biopsies to dermatologists may be a cost-effective strategy.

Human Migration and Leishmaniasis—On the Move

Abstract Full Text
JAMA Dermatol. 2016;152(4):373-374. doi:10.1001/jamadermatol.2015.4765

This Viewpoint highlights the importance of screening refugees from leishmaniasis-endemic areas to prevent the spread of this disease.

Editorial

Genetic Testing for Melanoma—Where Are We With Moderate-Penetrance Genes?

Abstract Full Text
JAMA Dermatol. 2016;152(4):375-376. doi:10.1001/jamadermatol.2015.4359

New Insights Into the Relationship Between the Skin and Endocrine Disorders

Abstract Full Text
JAMA Dermatol. 2016;152(4):377-379. doi:10.1001/jamadermatol.2015.4500
Original Investigation

Cutaneous Findings and Systemic Associations in Women With Polycystic Ovary Syndrome

Abstract Full Text
free access
JAMA Dermatol. 2016;152(4):391-398. doi:10.1001/jamadermatol.2015.4498

This cross-sectional study of a racially diverse sample of women identifies cutaneous and systemic features of polycystic ovary syndrome that help distinguish those who do and do not meet the diagnostic criteria.

Insulin Resistance and Metabolic Syndrome in Young Men With Acne

Abstract Full Text
free access
JAMA Dermatol. 2016;152(4):399-404. doi:10.1001/jamadermatol.2015.4499

This cross-sectional study examines whether postadolescent male patients with acne more commonly have insulin resistance.

Prevalence of MITF p.E318K in Patients With Melanoma Independent of the Presence of CDKN2A Causative Mutations

Abstract Full Text
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JAMA Dermatol. 2016;152(4):405-412. doi:10.1001/jamadermatol.2015.4356

This observational study examines the role of the MITF p.E318K variant in Spanish patients with melanoma, including clinical and phenotypic features.

Total Nevi, Atypical Nevi, and Melanoma Thickness: An Analysis of 566 Patients at 2 US Centers

Abstract Full Text
free access
JAMA Dermatol. 2016;152(4):413-418. doi:10.1001/jamadermatol.2016.0027

This survey study of patients with melanoma examines the association between age and the number of total nevi and atypical nevi and explores whether there was a relationship between total nevi or atypical nevi and tumor thickness, controlling for multiple variables.

Risk Factors for Cutaneous Squamous Cell Carcinoma Recurrence, Metastasis, and Disease-Specific Death: A Systematic Review and Meta-analysis

Abstract Full Text
free access
JAMA Dermatol. 2016;152(4):419-428. doi:10.1001/jamadermatol.2015.4994

This meta-analysis of observational studies summarizes risk factors for recurrence and metastasis of cutaneous squamous cell carcinoma, and risk for disease-specific death.

Risk of Major Adverse Cardiovascular Events and All-Cause Mortality in Patients With Hidradenitis Suppurativa

Abstract Full Text
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JAMA Dermatol. 2016;152(4):429-434. doi:10.1001/jamadermatol.2015.6264

This cohort study uses Danish National Registry data to compare the risk of cardiovascular events among patients with hidradenitis suppurativa, severe psoriasis, and healthy individuals.

Intrafamily and Interfamilial Phenotype Variation and Immature Immunity in Patients With Netherton Syndrome and Finnish SPINK5 Founder Mutation

Abstract Full Text
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JAMA Dermatol. 2016;152(4):435-442. doi:10.1001/jamadermatol.2015.5827

This cohort study evaluates the association of the SPINK5 mutation with the phenotype of Netherton syndrome (NS) and the extent of immunologic deficiencies in Finnish patients with NS.

Development and Psychometric Validation of the FACE-Q Skin, Lips, and Facial Rhytids Appearance Scales and Adverse Effects Checklists for Cosmetic Procedures

Abstract Full Text
free access
JAMA Dermatol. 2016;152(4):443-451. doi:10.1001/jamadermatol.2016.0018

This study describes the development and psychometric evaluation of 8 appearance scales and 2 adverse effects checklists for use in minimally invasive cosmetic procedures.

Brief Report

Effects of Combined Treatment With Arsenic Trioxide and Itraconazole in Patients With Refractory Metastatic Basal Cell Carcinoma

Abstract Full Text
JAMA Dermatol. 2016;152(4):452-456. doi:10.1001/jamadermatol.2015.5473

This case series reports the effects of treatment with arsenic trioxide and itraconazole on GLI messenger RNA expression in 5 patients with metastatic basal cell carcinoma who experienced disease progression despite treatment with Smoothened inhibitors.

JAMA Dermatology Clinicopathological Challenge

A 50-Year-Old Woman With Reticulate Hyperpigmentation

Abstract Full Text
JAMA Dermatol. 2016;152(4):461-462. doi:10.1001/jamadermatol.2015.5095

A 50-year-old woman presented with a slowly progressive red to brown pruritic hyperkeratotic papules and reticulated hyperpigmentation involving her face, neck, chest, back, and upper and lower extremities; she had been previously diagnosed with Darier disease. What is your diagnosis?

A Discordant Cutaneous Eruption in a Neonatal Twin

Abstract Full Text
JAMA Dermatol. 2016;152(4):463-464. doi:10.1001/jamadermatol.2015.5050

A male neonate born prematurely at 27 weeks’ gestational age had a erythematous eruption at birth, exhibiting 100 to 200 pink papules, 0.05 to 0.2 cm in size, distributed on the trunk, extensor upper arms, and upper legs. What is your diagnosis?

A Patient With Blue Ears

Abstract Full Text
JAMA Dermatol. 2016;152(4):465-466. doi:10.1001/jamadermatol.2015.4861

A 65-year-old woman presented with a 5-year history of increasing blue discoloration of her ears; she had mild knee arthralgia and was seeing an ophthalmologist annually regarding brown spots on both eyes diagnosed as conjunctival nevi. What is your diagnosis?

Research Letter

Repetitive Application of Sunscreen Containing Titanium Dioxide Nanoparticles on Human Skin

Abstract Full Text
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JAMA Dermatol. 2016;152(4):470-472. doi:10.1001/jamadermatol.2015.5944

This study examines the relative risk of skin penetration by nanoscale TiO2 nanoparticles in healthy fair-skinned individuals.

Ankle Range of Motion, Leg Pain, and Leg Edema Improvement in Patients With Venous Leg Ulcers

Abstract Full Text
free access
JAMA Dermatol. 2016;152(4):472-474. doi:10.1001/jamadermatol.2015.5637

This pilot study examines the effectiveness of compression therapy in treating pain, neuropathy, and reduced ankle range of motion in patients with venous leg ulcers.

Dirty Dots as a Normal Trichoscopic Finding in the Elderly Scalp

Abstract Full Text
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JAMA Dermatol. 2016;152(4):474-476. doi:10.1001/jamadermatol.2015.5545

This study reviews the trichoscopic images in the scalps of elderly women and assesses them for dirty dots.

Effect of Microneedle Pretreatment on Topical Anesthesia: A Randomized Clinical Trial

Abstract Full Text
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JAMA Dermatol. 2016;152(4):476-477. doi:10.1001/jamadermatol.2015.5544

This study randomized healthy patients to real vs sham microneedling on opposite arms to evaluate effects of the pretreatment on topical anesthesia with lidocaine cream, 4%.

Association of Dermatology Consultation With Accuracy of Cutaneous Disorder Diagnoses in Hospitalized Patients: A Multicenter Analysis

Abstract Full Text
free access
JAMA Dermatol. 2016;152(4):477-480. doi:10.1001/jamadermatol.2015.5098

This study examines hospitalist dermatology consultative services and accuracy of diagnosis of cutaneous dissorders in hospitalized patients.

FLT3 Inhibitor–Associated Neutrophilic Dermatoses

Abstract Full Text
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JAMA Dermatol. 2016;152(4):480-482. doi:10.1001/jamadermatol.2015.6121

This study presents 3 cases of FLT3 inhibitor–associated neutrophilic dermatoses.

Observation

Acute Generalized Pustular Psoriasis Treated With the IL-17A Antibody Secukinumab

Abstract Full Text
free access
JAMA Dermatol. 2016;152(4):482-484. doi:10.1001/jamadermatol.2015.4686

This case report describes rapid improvement of acute generalized pustular psoriasis treated with the interleukin 17A antibody secukinumab.

Well-Differentiated Syringofibrocarcinoma in a Patient With Clouston Syndrome

Abstract Full Text
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JAMA Dermatol. 2016;152(4):484-486. doi:10.1001/jamadermatol.2015.4496

This case report describes well-differentiated syringofibrocarcinoma in a patient with Clouston syndrome.

Perianal Dermatophytosis During Secukinumab Therapy for Plaque Psoriasis

Abstract Full Text
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JAMA Dermatol. 2016;152(4):486-487. doi:10.1001/jamadermatol.2015.4992

This case report describes 2 patients who developed perianal dermatophytosis during secukinumab therapy for plaque psoriasis.

Cutaneous T-Cell Lymphoma Misdiagnosed as Lipodermatosclerosis

Abstract Full Text
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JAMA Dermatol. 2016;152(4):487-488. doi:10.1001/jamadermatol.2015.6106

This case report describes an occurrence of cutaneous T-cell lymphoma misdiagnosed as lipodermatosclerosis.

Treatment of Eosinophilic Fasciitis With Sirolimus

Abstract Full Text
free access
JAMA Dermatol. 2016;152(4):488-490. doi:10.1001/jamadermatol.2016.0048

This case report describes the treatment of eosinophilic fasciitis with sirolimus.

Topical Ruxolitinib for the Treatment of Alopecia Universalis

Abstract Full Text
free access
JAMA Dermatol. 2016;152(4):490-491. doi:10.1001/jamadermatol.2015.4445

This case report describes effective use of topical ruxolitinib for treatment of alopecia universalis.

Misdiagnosed Periocular Pyoderma Gangrenosum Requiring Ectropion Repair With Development of Second Lesion of Pyoderma Gangrenosum at Graft Site

Abstract Full Text
free access
JAMA Dermatol. 2016;152(4):491-492. doi:10.1001/jamadermatol.2016.0062

This case report describes misdiagnosed periocular pyoderma gangrenosum requiring ectropion repair and the development of second lesion of pyoderma gangrenosum at the graft site.

Tofacitinib Citrate for the Treatment of Nail Dystrophy Associated With Alopecia Universalis

Abstract Full Text
free access
JAMA Dermatol. 2016;152(4):492-493. doi:10.1001/jamadermatol.2015.3772

This report of 3 cases describes remission of nail dystrophy associated with alopecia universalis after 5 to 6 months of treatment with tofacitinib citrate.

Comment & Response

Competing Risk of Death in Kaplan-Meier Curves When Analyzing Subsequent Keratinocyte Cancer

Abstract Full Text
JAMA Dermatol. 2016;152(4):493-494. doi:10.1001/jamadermatol.2015.5152

Competing Risk of Death in Kaplan-Meier Curves When Analyzing Subsequent Keratinocyte Cancer—Reply

Abstract Full Text
JAMA Dermatol. 2016;152(4):494-495. doi:10.1001/jamadermatol.2015.5153
Notable Notes

The Quest for the Ultimate Skin-Lightening Agent

Abstract Full Text
JAMA Dermatol. 2016;152(4):372. doi:10.1001/jamadermatol.2015.4243

Stereoscopic Cards in Early 20th Century Dermatologic Education

Abstract Full Text
JAMA Dermatol. 2016;152(4):374. doi:10.1001/jamadermatol.2015.3207

The Bard’s Blunder—Debunking the Myth Around Rhinophyma

Abstract Full Text
JAMA Dermatol. 2016;152(4):379. doi:10.1001/jamadermatol.2015.4240

Dermatologic Ailments in the White House

Abstract Full Text
JAMA Dermatol. 2016;152(4):398. doi:10.1001/jamadermatol.2015.3647

Syphilis, a Disfiguring Disease

Abstract Full Text
JAMA Dermatol. 2016;152(4):404. doi:10.1001/jamadermatol.2015.4242

Dermatologic Etymology: Descriptive Terms of Color

Abstract Full Text
JAMA Dermatol. 2016;152(4):428. doi:10.1001/jamadermatol.2015.3152

The Emperor’s Itch

Abstract Full Text
JAMA Dermatol. 2016;152(4):451. doi:10.1001/jamadermatol.2015.4241

The Purple Dye That Heals

Abstract Full Text
JAMA Dermatol. 2016;152(4):495. doi:10.1001/jamadermatol.2015.4239
JAMA Dermatology Masthead

JAMA Dermatology

Abstract Full Text
free access
JAMA Dermatol. 2016;152(4):480-482. doi:10.1001/jamadermatol.2015.3248
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