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October 2021 - January 1920




October 2021, Vol 157, No. 10, Pages 1152-1246


Sentinel Lymph Node Biopsy in Cutaneous Melanoma—Where Do We Stand?

Abstract Full Text
JAMA Dermatol. 2021;157(10):1159-1160. doi:10.1001/jamadermatol.2021.3048

This Viewpoint examines the utility of sentinel lymph node biopsy in the treatment of cutaneous melanoma.


Clinical Evidence on “Watchful Waiting” in Basal Cell Carcinoma

Abstract Full Text
JAMA Dermatol. 2021;157(10):1161-1162. doi:10.1001/jamadermatol.2021.3019
Original Investigation

Efficacy and Safety of Abrocitinib in Combination With Topical Therapy in Adolescents With Moderate-to-Severe Atopic Dermatitis: The JADE TEEN Randomized Clinical Trial

Abstract Full Text
open access
JAMA Dermatol. 2021;157(10):1165-1173. doi:10.1001/jamadermatol.2021.2830

This randomized clinical trial examines the efficacy and safety of abrocitinib plus topical therapy in adolescents with moderate-to-severe atopic dermatitis.

Evaluation of Watchful Waiting and Tumor Behavior in Patients With Basal Cell Carcinoma: An Observational Cohort Study of 280 Basal Cell Carcinomas in 89 Patients

Abstract Full Text
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JAMA Dermatol. 2021;157(10):1174-1181. doi:10.1001/jamadermatol.2021.3020

This cohort study evaluates reasons for watchful waiting and documents the natural course of basal cell carcinoma in patients who chose watchful waiting and reasons to initiate later treatment.

Assessment of Treatment Approaches and Outcomes in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: Insights From a Pan-European Multicenter Study

Abstract Full Text
JAMA Dermatol. 2021;157(10):1182-1190. doi:10.1001/jamadermatol.2021.3154

This cohort study examines culprit drugs and treatment strategies used in patients with Stevens-Johnson syndrome/toxic epidermal necrolysis in European countries.

Patterns of Atopic Eczema Disease Activity From Birth Through Midlife in 2 British Birth Cohorts

Abstract Full Text
JAMA Dermatol. 2021;157(10):1191-1199. doi:10.1001/jamadermatol.2021.2489

This cohort study follows members of 2 British population-based birth cohorts to examine whether early life risk factors and participant characteristics predict patterns of atopic eczema through midlife.

Association of Atopic Dermatitis and Mental Health Outcomes Across Childhood: A Longitudinal Cohort Study

Abstract Full Text
JAMA Dermatol. 2021;157(10):1200-1208. doi:10.1001/jamadermatol.2021.2657

This population-based birth cohort study examines the association between atopic dermatitis and symptoms of depression at multiple points across childhood and adolescence and explores the role of potential mediating factors.

Brief Report

Prevalence of Central Sensitization in Patients With Hidradenitis Suppurativa

Abstract Full Text
JAMA Dermatol. 2021;157(10):1209-1212. doi:10.1001/jamadermatol.2021.2918

This cross-sectional, case-control study assesses the prevalence of central sensitization in patients with hidradenitis suppurativa compared with sex- and age-matched controls in the Netherlands.

Patient Quality of Life After Interpolated Flap Repair of Nasal Mohs Surgery Defects: A Multicenter Prospective Cohort Study

Abstract Full Text
JAMA Dermatol. 2021;157(10):1213-1216. doi:10.1001/jamadermatol.2021.3161

This cohort study uses the Skin Cancer Index to evaluate patient quality of life after Mohs micrographic surgery and interpolation flap reconstruction for patients with nasal skin cancers.

Consensus Statement

Consensus-Based Recommendations on the Prevention of Squamous Cell Carcinoma in Solid Organ Transplant Recipients: A Delphi Consensus Statement

Abstract Full Text
JAMA Dermatol. 2021;157(10):1219-1226. doi:10.1001/jamadermatol.2021.3180

This review reports the development and results of the Strategies for the Prevention of Skin Cancer in Solid Organ Transplant Recipients Delphi study.

Images in Dermatology

Primary Cutaneous Endometriosis Presenting as an Umbilical Nodule

Abstract Full Text
JAMA Dermatol. 2021;157(10):1227. doi:10.1001/jamadermatol.2021.2571

This case report describes an umbilical mass that had been present for a year.

Intertriginous Xanthomas—Pathognomonic Cutaneous Markers of Homozygous Familial Hypercholesterolemia

Abstract Full Text
JAMA Dermatol. 2021;157(10):1228. doi:10.1001/jamadermatol.2021.3060

This case report describes yellow papules coalescing into plaques involving the medial and lateral canthi of eyes, finger web spaces of both hands, antecubital fossae, and nodular swellings over the elbows.

JAMA Dermatology Clinicopathological Challenge

Indurated Plaques With Telangiectasias on the Lower Limbs

Abstract Full Text
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JAMA Dermatol. 2021;157(10):1229-1230. doi:10.1001/jamadermatol.2021.3051

A woman in her 70s presents with a 3-month history of episodic fever and painless cutaneous lesions on her lower limbs. What is your diagnosis?

Ichthyosiform Rashes and Joint Pain in a Boy

Abstract Full Text
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JAMA Dermatol. 2021;157(10):1231-1232. doi:10.1001/jamadermatol.2021.3498

A school-aged boy presents with generalized erythematous rashes for 4 years and ichthyosiform brownish plaques on his lower extremities and multiple erythematous confluent papules and plaques on his trunk and face. What is your diagnosis?

Research Letter

Patient-Reported Outcome Measures as Complementary Information to Clinician-Reported Outcome Measures in Patients With Psoriasis

Abstract Full Text
JAMA Dermatol. 2021;157(10):1236-1237. doi:10.1001/jamadermatol.2021.3341

This cross-sectional study assesses patient-reported outcome measures as a complement to clinician-reported outcome measures in psoriasis treatment.

Postmarketing Cases of Enfortumab Vedotin–Associated Skin Reactions Reported as Stevens-Johnson Syndrome or Toxic Epidermal Necrolysis

Abstract Full Text
JAMA Dermatol. 2021;157(10):1237-1239. doi:10.1001/jamadermatol.2021.3450

This case series study uses data from the FDA Adverse Event Reporting System to investigate a potential association between enfortumab vedotin treatment and Stevens-Johnson Syndrome and toxic epidermal necrolysis.

Out-of-Pocket Costs of Specialty Medications for Psoriasis and Psoriatic Arthritis Treatment in the Medicare Population

Abstract Full Text
JAMA Dermatol. 2021;157(10):1239-1241. doi:10.1001/jamadermatol.2021.3616

This cross-sectional study examines out-of-pocket costs associated with specialty medications for psoriasis and psoriatic arthritis among Medicare beneficiaries.


Role of Eosinophils in Angiolymphoid Hyperplasia With Eosinophilia

Abstract Full Text
JAMA Dermatol. 2021;157(10):1241-1243. doi:10.1001/jamadermatol.2021.2732

This case report describes a man in his 50s with a 14-year history of angiolymphoid hyperplasia with eosinophilia and nodular tumors in both preauricular regions.

Epidermolysis Bullosa Pruriginosa Treated With Baricitinib

Abstract Full Text
JAMA Dermatol. 2021;157(10):1243-1244. doi:10.1001/jamadermatol.2021.3174

This case report describes a 40-year-old man who had blistering and trauma-induced erosions shortly after birth and nodular prurigo-like lesions during his teenage years who presented with erythematous lichenified papules and nodules with crusts and milia over the scalp, trunk, and extremities.

Comment & Response

An Abscess Is Not a Descriptive Term but an Entity With a Universally Accepted Definition—A Clarification on Semantics

Abstract Full Text
JAMA Dermatol. 2021;157(10):1244-1245. doi:10.1001/jamadermatol.2021.3169

An Abscess Is Not a Descriptive Term but an Entity With a Universally Accepted Definition—A Clarification on Semantics—Reply

Abstract Full Text
JAMA Dermatol. 2021;157(10):1245-1246. doi:10.1001/jamadermatol.2021.2495

Errors in Table 1, Figure 3, and Results

Abstract Full Text
free access
JAMA Dermatol. 2021;157(10):1246. doi:10.1001/jamadermatol.2021.4398

Errors in Abstract and Results Section

Abstract Full Text
free access
JAMA Dermatol. 2021;157(10):1246. doi:10.1001/jamadermatol.2021.4420
JAMA Dermatology Masthead

JAMA Dermatology

Abstract Full Text
free access
JAMA Dermatol. 2021;157(10):1152. doi:10.1001/jamadermatol.2020.3908