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October 13, 2021
Editorial

Targeting Immune Checkpoints and Cytokines to Protect From Psoriasis Relapse

Abstract Full Text
JAMA Dermatol. Published online October 13, 2021. doi:10.1001/jamadermatol.2021.3491
Original Investigation

Effect of Costimulatory Blockade With Abatacept After Ustekinumab Withdrawal in Patients With Moderate to Severe Plaque Psoriasis: The PAUSE Randomized Clinical Trial

Abstract Full Text
open access
JAMA Dermatol. Published online October 13, 2021. doi:10.1001/jamadermatol.2021.3492

This parallel-design, doube-blind randomized clinical trial evaluates whether abatacept could prevent psoriasis relapse after discontinuation of ustekinumab treatment in adults with plaque psoriasis.

Brief Report

Homozygous MEFV Gene Variant and Pyrin-Associated Autoinflammation With Neutrophilic Dermatosis: A Family With a Novel Autosomal Recessive Mode of Inheritance

Abstract Full Text
JAMA Dermatol. Published online October 13, 2021. doi:10.1001/jamadermatol.2021.3899

This case series study examines the DNA of siblings and parents from a consanguineous family to find the genetic basis for pyrin-associated autoinflammation with neutrophilic dermatosis and to prescribe genotype-guided treatment.

Images in Dermatology

Perianal Chancres of Primary Syphilis

Abstract Full Text
JAMA Dermatol. Published online October 13, 2021. doi:10.1001/jamadermatol.2021.3763

This case report describes multiple small, punched-out ulcers within an erythematous and hypopigmented plaque in the perianal area.

JAMA Dermatology Clinicopathological Challenge

Widespread Erythematous Plaques With Prominent Telangiectases

Abstract Full Text
has active quiz
JAMA Dermatol. Published online October 13, 2021. doi:10.1001/jamadermatol.2021.4068

A woman in her 50s with a history of nasal-type natural killer/T-cell lymphoma and chronic pulmonary coccidiomycosis was admitted for fever, hypotension, and asymptomatic widespread rash. What is your diagnosis?

JAMA Dermatology Patient Page

Stasis Dermatitis

Abstract Full Text
free access
JAMA Dermatol. Published online October 13, 2021. doi:10.1001/jamadermatol.2021.3475

This Patient Page describes the symptoms, possible causes, and treatment of stasis dermatitis.

Observation

Evaluation and Treatment of Febrile Ulceronecrotic Mucha-Habermann Disease With Ruxolitinib and Tocilizumab as Guided by Cytokine Profile

Abstract Full Text
JAMA Dermatol. Published online October 13, 2021. doi:10.1001/jamadermatol.2021.4047

This case report describes treatment with tocilizumab and ruxolitinib for febrile ulceronecrotic Mucha-Habermann disease.

October 6, 2021
Original Investigation

Assessment of Clinical and Laboratory Use of the Cutaneous Direct Immunofluorescence Assay

Abstract Full Text
JAMA Dermatol. Published online October 6, 2021. doi:10.1001/jamadermatol.2021.3892

This quality improvement study examines the need for specific vs full-panel antibody testing in patients with skin diseases.

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