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September 15, 2021
Original Investigation

Sirolimus (Rapamycin) for Slow-Flow Malformations in Children: The Observational-Phase Randomized Clinical PERFORMUS Trial

Abstract Full Text
JAMA Dermatol. Published online September 15, 2021. doi:10.1001/jamadermatol.2021.3459

This randomized clinical trial assesses the efficacy and safety of sirolimus among children with slow-flow vascular malformations to better delineate the indications for treatment.

Brief Report

Inflation-Adjusted Trends in Medicare Reimbursement for Common Dermatologic Procedures, 2007-2021

Abstract Full Text
JAMA Dermatol. Published online September 15, 2021. doi:10.1001/jamadermatol.2021.3453

This cross-sectional study identifies trends in Medicare reimbursement for 46 common dermatologic procedures from 2007 to 2021.

Images in Dermatology

Cutaneous Lupus Erythematosus of the Vulvar Skin

Abstract Full Text
JAMA Dermatol. Published online September 15, 2021. doi:10.1001/jamadermatol.2021.3293

This case report describes scarred erythematous patches on the labia majora, labia minora, and inguinal folds with no mucosal involvement.

Research Letter

Out-of-Pocket Costs of Specialty Medications for Psoriasis and Psoriatic Arthritis Treatment in the Medicare Population

Abstract Full Text
JAMA Dermatol. Published online September 15, 2021. doi:10.1001/jamadermatol.2021.3616

This cross-sectional study examines out-of-pocket costs associated with specialty medications for psoriasis and psoriatic arthritis among Medicare beneficiaries.

September 8, 2021
Editorial

Clinical Evidence on “Watchful Waiting” in Basal Cell Carcinoma

Abstract Full Text
JAMA Dermatol. Published online September 8, 2021. doi:10.1001/jamadermatol.2021.3019
Original Investigation

Evaluation of Watchful Waiting and Tumor Behavior in Patients With Basal Cell Carcinoma: An Observational Cohort Study of 280 Basal Cell Carcinomas in 89 Patients

Abstract Full Text
JAMA Dermatol. Published online September 8, 2021. doi:10.1001/jamadermatol.2021.3020

This cohort study evaluates reasons for watchful waiting and documents the natural course of basal cell carcinoma in patients who chose watchful waiting and reasons to initiate later treatment.

Brief Report

UBA1 Variations in Neutrophilic Dermatosis Skin Lesions of Patients With VEXAS Syndrome

Abstract Full Text
JAMA Dermatol. Published online September 8, 2021. doi:10.1001/jamadermatol.2021.3344

This case series study of 8 French men examines clinical and pathological skin manifestations and their pathophysiology in VEXAS syndrome.

JAMA Dermatology Clinicopathological Challenge

Ichthyosiform Rashes and Joint Pain in a Boy

Abstract Full Text
has active quiz
JAMA Dermatol. Published online September 8, 2021. doi:10.1001/jamadermatol.2021.3498

A school-aged boy presents with generalized erythematous rashes for 4 years and ichthyosiform brownish plaques on his lower extremities and multiple erythematous confluent papules and plaques on his trunk and face. What is your diagnosis?

Research Letter

Patient-Reported Outcome Measures as Complementary Information to Clinician-Reported Outcome Measures in Patients With Psoriasis

Abstract Full Text
JAMA Dermatol. Published online September 8, 2021. doi:10.1001/jamadermatol.2021.3341

This cross-sectional study assesses patient-reported outcome measures as a complement to clinician-reported outcome measures in psoriasis treatment.

Postmarketing Cases of Enfortumab Vedotin–Associated Skin Reactions Reported as Stevens-Johnson Syndrome or Toxic Epidermal Necrolysis

Abstract Full Text
JAMA Dermatol. Published online September 8, 2021. doi:10.1001/jamadermatol.2021.3450

This case series study uses data from the FDA Adverse Event Reporting System to investigate a potential association between enfortumab vedotin treatment and Stevens-Johnson Syndrome and toxic epidermal necrolysis.

September 1, 2021
Original Investigation

Patterns of Atopic Eczema Disease Activity From Birth Through Midlife in 2 British Birth Cohorts

Abstract Full Text
JAMA Dermatol. Published online September 1, 2021. doi:10.1001/jamadermatol.2021.2489

This cohort study follows members of 2 British population-based birth cohorts to examine whether early life risk factors and participant characteristics predict patterns of atopic eczema through midlife.

Association of Atopic Dermatitis and Mental Health Outcomes Across Childhood: A Longitudinal Cohort Study

Abstract Full Text
JAMA Dermatol. Published online September 1, 2021. doi:10.1001/jamadermatol.2021.2657

This population-based birth cohort study examines the association between atopic dermatitis and symptoms of depression at multiple points across childhood and adolescence and explores the role of potential mediating factors.

Consensus Statement

Consensus-Based Recommendations on the Prevention of Squamous Cell Carcinoma in Solid Organ Transplant Recipients: A Delphi Consensus Statement

Abstract Full Text
JAMA Dermatol. Published online September 1, 2021. doi:10.1001/jamadermatol.2021.3180

This review reports the development and results of the Strategies for the Prevention of Skin Cancer in Solid Organ Transplant Recipients Delphi study.

Images in Dermatology

Intertriginous Xanthomas—Pathognomonic Cutaneous Markers of Homozygous Familial Hypercholesterolemia

Abstract Full Text
JAMA Dermatol. Published online September 1, 2021. doi:10.1001/jamadermatol.2021.3060

This case report describes yellow papules coalescing into plaques involving the medial and lateral canthi of eyes, finger web spaces of both hands, antecubital fossae, and nodular swellings over the elbows.

Research Letter

Prevalence and Characterization of Itch in Pachyonychia Congenita

Abstract Full Text
JAMA Dermatol. Published online September 1, 2021. doi:10.1001/jamadermatol.2021.3335

This survey study examines the prevalence and characteristics of itch in pachyonychia congenita.

Observation

Epidermolysis Bullosa Pruriginosa Treated With Baricitinib

Abstract Full Text
JAMA Dermatol. Published online September 1, 2021. doi:10.1001/jamadermatol.2021.3174

This case report describes a 40-year-old man who had blistering and trauma-induced erosions shortly after birth and nodular prurigo-like lesions during his teenage years who presented with erythematous lichenified papules and nodules with crusts and milia over the scalp, trunk, and extremities.

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