The fountain of youth or potent neurotoxin? Botulinum toxin represents both. It has long been known that victims of facial paralysis present a more youthful visage on the paralyzed side, and minimizing muscular contractions can help prevent the formation of folds and rhytids in facial skin. The biochemical impact of muscular contractions, however, has largely been overlooked and represents a fascinating new field in the understanding of the aging process. That injections affect far more than muscular contraction, and actually improve collagen and skin quality, is just now being investigated as a valid histologic response.
Winslow CP. Furthering the Understanding of Actions of Botulinum Toxin A. JAMA Facial Plast Surg. 2015;17(4):263–264. doi:10.1001/jamafacial.2015.0567
Browse and subscribe to JAMA Network podcasts!
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: