From Beckman Laser Institute and Medical Clinic and the Departments
of Dermatology and Surgery, University of California, Irvine (Drs
Kelly, Majaron, and Nelson); and Quantum Optics Laboratory, Jozef
Stefan Institute, Ljubljana, Slovenia (Dr Majaron).
For centuries, patients
and physicians have sought a safe and effective method for treating
skin changes associated with photoaging. Currently, a variety of
modalities are used to treat facial rhytids, including dermabrasion,
chemical peels, and laser skin resurfacing (LSR). Although these
modalities are relatively effective for rhytid reduction, epidermal
disruption or removal results in an open wound that places the patient
at risk for bacterial, viral, and fungal infections. Abnormal or
delayed wound healing may result in skin dyspigmentation and scarring.
In addition, the wound resolves with significant erythema that often
lasts for weeks or months and is cosmetically troubling to patients
(Figure 1). The ideal method of
skin rejuvenation would achieve optimal cosmetic improvement of
photodamage while minimizing wound care and the risk of adverse
Kelly KM, Majaron B, Nelson JS. Nonablative Laser and Light RejuvenationThe Newest Approach to Photodamaged Skin. Arch Facial Plast Surg. 2001;3(4):230–235. doi:
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