Author Affiliations: Group Health Research Institute, Group Health Cooperative, Seattle, Washington (Dr Newton), and Department of Medicine, University of California, San Francisco and Medicine Service, San Francisco VA Medical Center, California (Dr Grady).
Every woman who lives long enough will go through the menopause transition; approximately 80% will experience hot flashes and night sweats, and approximately 20% will experience sufficient discomfort to seek treatment.1 Also, women lose bone mass at an accelerated rate of approximately 2% per year during the menopause transition, resulting in increased risk of osteoporosis and fractures later in life.2
Katherine M. Newton, Deborah Grady. Soy Isoflavones for Prevention of Menopausal Bone Loss and Vasomotor SymptomsComment on “Soy Isoflavones in the Prevention of Menopausal Bone Loss and Menopausal Symptoms”. Arch Intern Med. 2011;171(15):1369–1370. doi:10.1001/archinternmed.2011.331