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Editor's Correspondence
November 9, 2009

Low-Carbohydrate Diet and Blood Lipid Levels: How Good and How Fast?—Reply

Author Affiliations

Copyright 2009 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2009

Arch Intern Med. 2009;169(20):1930-1931. doi:10.1001/archinternmed.2009.411

In reply

We thank Giugliano and colleagues for their kind words on the possible value of our study. We agree absolutely that the study was small, of short duration, and extreme in terms of carbohydrate restriction. As Giugliano and colleagues rightly noted, the aim of the study was proof of principle that high-fat and high-protein diets of plant origin may have advantages over animal product–based diets in terms of LDL-C level reduction, with benefits also for the total–high-density lipoprotein cholesterol ratio and blood pressure reduction.