We agree with Simon's comments that the use of evoked potentials may be of value in diagnosing sarcoidosis. In our own study, we did not routinely use multimodality evoked potentials. We agree that there is literature suggesting that visual, auditory, and somatosensory evoked potentials can identify neurosarcoidosis when other techniques have failed to do so. It appears that this technique is more sensitive than neuroradiological films or lumbar puncture. We would like to mention a recent article by Gott et al1 that describes 25 patients with no evidence of neurosarcoidosis. Twelve had abnormal findings of multimodality evoked potentials, suggesting a much higher incidence of these abnormalities than is shown by clinical evidence from neurosarcoidosis. It is not yet clear to us whether a patient with an abnormal evoked potential finding but with no other evidence of neurosarcoidosis should be treated.
Baughman RP, Lower EE. Multimodality Evoked Potentials in the Diagnosis and Management of Neurological Sarcoidosis. Arch Intern Med. 1998;158(9):1036. doi:
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