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Invited Commentary
June 11, 2012

Adolescent and Adult Pharyngitis: More Than “Strep Throat”: Comment on “Large-Scale Validation of the Centor and McIsaac Scores to Predict Group A Streptococcal Pharyngitis”

Author Affiliations

Author Affiliation: Department of Internal Medicine, University of Alabama, Huntsville.

Arch Intern Med. 2012;172(11):852-853. doi:10.1001/archinternmed.2012.1741

In this issue of the Archives, Fine and colleagues1 report a major validation of clinical prediction rules for predicting group A streptococcal (GAS) pharyngitis. They examine the prediction model that I and my research team2 first reported in 1981 and the modification (incorporating age into the decision rule) that McIsaac et al3 reported in 1998. This validation confirms a recent meta-analysis that arrived at the same finding.4