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Invited Commentary
Dec 10/24, 2012

Moderate Renal Impairment and Risk of Bleeding With Anticoagulation: Comment on “Enoxaparin Outcomes in Patients With Moderate Renal Impairment”

Author Affiliations

Author Affiliation: Department of Medicine, University of California, San Francisco.

Arch Intern Med. 2012;172(22):1718-1720. doi:10.1001/2013.jamainternmed.456

Bleeding is the most feared complication of anticoagulant therapy and, unfortunately, it is not uncommon. The 2011-2012 National Patient Safety Goals mandate efforts to “reduce the likelihood of patient harm associated with the use of anticoagulant therapy.”1 This is a call for coordinated efforts to decrease adverse events related to anticoagulant therapy, with recommendations for improved oversight and evidence-based management of these agents in the inpatient and outpatient settings.