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Invited Commentary
Jan 28, 2013

Here We Go Again—Blood Transfusion Kills Patients?Comment on “Association of Blood Transfusion With Increased Mortality in Myocardial Infarction: A Meta-analysis and Diversity-Adjusted Study Sequential Analysis”

JAMA Intern Med. 2013;173(2):139-141. doi:10.1001/jamainternmed.2013.2855

Do blood transfusions kill more patients with an acute myocardial infarction than anemia? Chatterjee and colleagues1 would have you believe that they do. We remain unconvinced.

In reviewing the study, we first wondered whether the authors asked the right question. As physicians, we believe that profound anemia is life threatening,2 and as a consequence transfusions in many patients are life saving. Therefore, we expected that more nuanced, clinically relevant questions would be addressed.

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