Author Affiliations: General Practice and Primary Health Care, University of Ghent, Ghent, Belgium.
One of the merits of Robert Centor is that in 1981, he and his colleagues1 already showed that the prevalence of group A β-hemolytic streptococci (GAS) in the throat is 56% when the following 4 Centor criteria are present: fever of 38.5°C or higher, tonsillar exudate, absence of cough, and enlarged cervical glands. The validation of the Centor and McIsaac scores by Fine et al2 showed comparable results.
Matthys J, De Meyere M. Clinical Scores to Predict Streptococcal Pharyngitis: Believers and Nonbelievers. JAMA Intern Med. 2013;173(1):77–78. doi:10.1001/2013.jamainternmed.741
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