We read with interest the excellent article by Mueller and colleagues1 about hospital-based medication reconciliation practices. We would like to offer some elements about our own experience. The evaluation of the potential clinical impact of the unintentional discrepancies identified and corrected during medication reconciliation process is particularly of high interest. Recently, we have set up conciliation at admission within our hospital and estimated in parallel the potential clinical significance of identified unintentional discrepancies by using a 3-category scale: level 1, “no potential harm”; level 2, “monitoring or intervention potentially required to preclude harm”; and level 3, “potential harm.”