Author Affiliations: Department of Thoracic and Cardiovascular Surgery (Drs Pattakos and Blackstone), Department of Cardiothoracic Anesthesia, Quality and Patient Safety Institute (Dr Koch), and Department of Quantitative Health Sciences (Dr Blackstone), Cleveland Clinic, Cleveland, Ohio.
We thank Dr Angouras for his insightful commentary on our recent publication on severe blood conservation.1 He states that:
It would be interesting to know whether the results attained in Jehovah's Witnesses are identical to matched non-Witnesses who were not transfused. Lack of pertinent data casts doubt on the external validity and, hence, the final conclusion of the study.
Pattakos G, Koch CG, Blackstone EH. Jehovah's Witnesses May Not Have Identical Outcomes With Nontransfused Non-Witnesses After Cardiac Surgery—Reply. JAMA Intern Med. 2013;173(3):248–249. doi:10.1001/jamainternmed.2013.2139
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