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Editor's Correspondence
April 8, 2013

DMAA as a Dietary Ingredient—Reply

Author Affiliations

Author Affiliation: Department of Medicine, Cambridge Health Alliance and Harvard Medical School, Cambridge, Massachusetts.

JAMA Intern Med. 2013;173(7):594-595. doi:10.1001/jamainternmed.2013.3776

In reply

Rodricks and Lumpkin argue that 1,3-dimethylamylamine (DMAA) does not possess amphetamine-like effects, is found in geranium, and has been documented to be safe. These are all inaccurate characterizations of the literature.

DMAA is a pharmaceutical patented by Eli Lilly & Co to possess the desirable properties of both ephedrine and amphetamine. An indirect sympathomimetic amine, DMAA has both vasoconstrictive properties and cardiovascular effects.