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Comment & Response
February 2014

Conflicts of Interest in Approvals of Food Additives

Author Affiliations
  • 1Science and Regulatory Affairs, The Grocery Manufacturers Association, Washington, DC
JAMA Intern Med. 2014;174(2):299. doi:10.1001/jamainternmed.2013.12720

To the Editor In concluding that financial conflicts of interest are ubiquitous in the conduct of “generally recognized as safe” (GRAS) determinations, Neltner et al1 fundamentally misunderstand the legal framework that governs the use of substances in food. The authors draw on principles regarding conflicts of interest that were articulated by the Institute of Medicine in the context of medical education, research, and practice. Nowhere do the authors explain why it is appropriate to apply those principles in the context of a GRAS determination by a food manufacturer. It is not appropriate.

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