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Editor's Correspondence
February 23, 1998

Sulfonylureas and Ischemic Heart Disease

Arch Intern Med. 1998;158(4):411-412. doi:

Readers of Dagogo-Jack and Santiago's1 excellent review of type 2 diabetes may be unaware that the embers of controversy regarding the effects of sulfonylureas on the heart in patients with type 2 diabetes, originally raised by the much maligned University Group Diabetes Program study,2 have been fanned by a series of basic science and animal experiments conducted over the past decade.3