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Editor's Correspondence
February 23, 1998

Sulfonylureas and Ischemic Heart Disease

Author Affiliations

Copyright 1998 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.1998

Arch Intern Med. 1998;158(4):411-412. doi:

In reply

Matz revisits the subject of possible cardiac effects of sulfonylureas and cites recent animal studies. Although there is experimental evidence that sulfonylureas might interfere with ischemic myocardial "preconditioning," there is also abundant evidence for antiarrhythmic effects of sulfonylureas in several animal models of ischemic injury.1-3

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