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Editor's Correspondence
March 9, 1998

The Obsolescence of Lactate Dehydrogenase Testing

Arch Intern Med. 1998;158(5):544. doi:

In reference to lactate dehydrogenase (LDH) testing1 as a useful component of assessing probability of myocardial injury, it seems long past due that routine measurement of LDH isoenzymes be discouraged if not altogether abandoned. After more than 10 years of attempting to make LDH isoenzymes a sensitive and specific test with varying assays, it continues to fall short of any appropriate standard.