Gross and Powe raise an excellent point and we have performed 2 additional analyses after removing patients who received coronary artery bypass graft surgery and those who received any cardiac surgery. In both sets of analyses, acute care hospital costs continued to be higher in patients with AF. For example, after removing patients who received coronary artery bypass graft surgery, 1-year acute care hospital costs were higher in those with AF (Table 1). Acute care costs at 1 year significantly higher (P<.05) in 5 of the 6 AF age-sex categories (Table 1). Costs were still significantly higher at years 2 and 3 in 3 of 6 age-sex categories in men and women. However, although higher in those with AF, differences were no longer significant in men aged 75 to 84 years at 2 years.
Wolf PA, Mitchell JB. Atrial Fibrillation: Mortality, Stroke, and Medical Costs. Arch Intern Med. 1998;158(20):2265–2266. doi:
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