We have started an open prospective study in 1997 and a 2-year follow-up in 1999 to examine the number of pills prescribed, drug intake frequency, and reasons for nonadherence to highly active antiretroviral therapy (HAART).1 The objective and design of our evaluation is similar to some aspects of the ATHENA Project.2 Patients with human immunodeficiency virus (HIV) were asked to complete an anonymous questionnaire about adherence to prescribed HAART in which daily intake frequency, number of pills to take, and reasons for missed drugs or intake were specified.
Paech V, Lorenzen T, Stoehr A, Plettenberg A. Adherence to HAART: Why Is It So Difficult? Arch Intern Med. 2002;162(10):1197–1198. doi:
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