[Skip to Navigation]
Clinical Observation
June 24, 2002

Brugada Syndrome: An Unusual Cause of Convulsive Syncope

Author Affiliations

From the Departments of Medicine, Case Western Reserve University, University Hospitals of Cleveland, Cleveland, Ohio (Dr Paydak), and Advocate Illinois Masonic Medical Center, Chicago, Ill (Drs Telfer, Kehoe, Balasubramanian, Narra, Ezri, Zheutlin, Maheshwari, Nazari, and Wang).

Arch Intern Med. 2002;162(12):1416-1419. doi:10.1001/archinte.162.12.1416

A patient who presented with a new apparent seizure was found to have abnormal electrocardiographic findings, with classic features of the Brugada syndrome. He had spontaneous episodes of nonsustained ventricular tachycardia, easily inducible ventricular fibrillation at electrophysiological study in the absence of structural heart disease, and a negative neurological evaluation. These findings suggested that sustained ventricular arrhythmias known to be associated with the Brugada syndrome and resultant cerebral hypoperfusion, rather than a primary seizure disorder, were responsible for the event. Patients with the Brugada syndrome often present with sudden death or with syncope resulting from ventricular arrhythmias. In consideration of its variability in presentation sometimes mimicking other disorders, primary care physicians and internists should be aware of its often transient electrocardiographic features.

Add or change institution