Misleading Report of Massive Bleeding in a Patient Taking Pentosan Polysulfate

I read with concern the article by Gill et al,¹ published in the July 22, 2002, issue of the ARCHIVES, which describes an episode of massive bleeding in a woman whose regular medications included pentosan polysulfate sodium (Elmiron; Alza Pharmaceuticals, Mountain View, Calif). This report is seriously misleading and raises an unnecessary and probably groundless alarm concerning pentosan polysulfate.