Dr Punnam asks if systemic corticosteroid or ICS use prior to admission for acute exacerbations of COPD influenced inpatient mortality. The objectives of our study1 were to obtain a generalizable estimate of in-hospital COPD mortality and to identify high-risk groups using readily available administrative data. Determining the impact of specific therapies on hospital outcomes was not one of our goals and unfortunately cannot be addressed with the data source used in our study (the Nationwide Inpatient Sample [NIS] does not contain information about medications on hospital admission).
Patil SP, Krishnan JA, Lechtzin N, Diette GB. In-Hospital Mortality and Long-term Use of Inhaled Corticosteroids—Reply. Arch Intern Med. 2004;164(2):222–223. doi:10.1001/archinte.164.2.222-b