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Comment & Response
April 2015

Sex-Specific Chest Pain Characteristics

Author Affiliations
  • 1Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands
  • 2Department of Cardiology, VU University Medical Center Amsterdam, Amsterdam, the Netherlands
JAMA Intern Med. 2015;175(4):650. doi:10.1001/jamainternmed.2014.8060

To the Editor Rubini Gimenez et al1 studied sex-specific chest pain characteristics (CPCs) with the objective of improving the management of women with suspected acute myocardial infarction (AMI). They collected an impressive number of baseline and chest pain characteristics in a large sample of patients with chest pain.

Unfortunately, the prevalence of CPCs in women was only compared with the prevalence of CPCs in men. Whether the prevalence of CPCs in women with AMI differed from women without AMI (and men with and without AMI) was not evaluated, while such an analysis would demonstrate which symptoms are related to AMI in women and which in men.

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