Cost-related nonadherence (CRN) is common, and one-third of older adults take less medication than prescribed to reduce out-of-pocket costs.1 Common strategies to reduce out-of-pocket costs include splitting pills, skipping doses, or delaying refills, all secondary forms of nonadherence.1 Less attention has been paid to “primary” nonadherence, ie, not even filling the prescription. This strategy is the most effective way to reduce out-of-pocket costs, and primary nonadherence is practiced by 10% to 20% of patients.2
Majumdar SR. Cost Sharing and the Initiation of Drug Therapy for the Chronically Ill—Invited Commentary. Arch Intern Med. 2009;169(8):748–749. doi:10.1001/archinternmed.2009.41
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