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Editor's Correspondence
September 28, 2009

Relationship Between Bone, Fracture, and Exercise: The Key Role of Vitamin D

Arch Intern Med. 2009;169(17):1633-1638. doi:10.1001/archinternmed.2009.322

Recently, Bischoff-Ferrari et al1 reported the results of an interesting meta-analysis on the efficacy of oral supplemental vitamin D in preventing nonvertebral fractures in older adults. The findings showed a dose-dependant protective effect of vitamin D against fractures, which was independent of additional calcium supplementation. A significant effect of supplementation was observed for a dose above 400 IU/d and reduced the nonvertebral fracture rate by 20%.1