Recently, Bischoff-Ferrari et al1 reported the results of an interesting meta-analysis on the efficacy of oral supplemental vitamin D in preventing nonvertebral fractures in older adults. The findings showed a dose-dependant protective effect of vitamin D against fractures, which was independent of additional calcium supplementation. A significant effect of supplementation was observed for a dose above 400 IU/d and reduced the nonvertebral fracture rate by 20%.1
Annweiler C, Beauchet O. Relationship Between Bone, Fracture, and Exercise: The Key Role of Vitamin D. Arch Intern Med. 2009;169(17):1633–1638. doi:10.1001/archinternmed.2009.322
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