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Invited Commentary
September 27, 2010

Risk of Diabetes and Cardiovascular Disease: Best to Return Back to the Basics: Comment on “Long-term Effects of a Lifestyle Intervention on Weight and Cardiovascular Risk Factors in Individuals With Type 2 Diabetes Mellitus”

Author Affiliations

Author Affiliation: Veterans Affairs Central California Healthcare System (VACCHCS) and Medical Education Program, University of California, San Francisco, Fresno.

Arch Intern Med. 2010;170(17):1575-1577. doi:10.1001/archinternmed.2010.333

The prevalence of type 2 DM is rapidly increasing throughout the world. Recent data from the Centers for Disease Control and Prevention indicate that by 2050 nearly 50 million Americans will have type 2 DM. Because the risk of macrovascular disease leading to myocardial infarction or stroke begins on average 6 to 8 years before the onset of clinical diabetes, there has been an ongoing search for novel markers for identification of individuals at high risk of developing type 2 DM.