Over the past 15 years, dialysis has been initiated at progressively higher levels of estimated kidney function. From 1995 through 2007, the average serum creatinine concentration at the time of initiation of dialysis decreased from 8.7 mg/dL to 6.3 mg/dL, with the average estimated glomerular filtration rate (eGFR) averaging 10.9 mL/min/1.73 m2 in 2007 and a full 50% of patients initiating dialysis with an eGFR of at least 10 mL/min/1.73 m2.1
Johansen KL. Time to Rethink the Timing of Dialysis Initiation. Arch Intern Med. 2011;171(5):382–383. doi:10.1001/archinternmed.2010.413
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