To the Editor It is with great interest that we read the article “Prescription Opioid Duration of Action and the Risk of Unintentional Overdose Among Patients Receiving Opioid Therapy” published in the April issue of JAMA Internal Medicine.1 Miller and colleagues used data from the Veterans Administration Healthcare system and found that patients initiating opioid therapy with long-acting opioids were more than twice as likely to overdose compared with those initiating therapy with short-acting opioids.
Xiulu Ruan, Jiang Wu, Alan David Kaye. Prescription Opioid Duration of Action and the Risk of Unintentional Overdose. JAMA Intern Med. 2015;175(9):1582–1583. doi:10.1001/jamainternmed.2015.3256