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Comment & Response
October 2015

Another Report of Familial Spontaneous Coronary Artery Dissection

Author Affiliations
  • 1School of Clinical Sciences at Monash Health, Monash University, Melbourne, Australia
  • 2Monash Heart, Monash Health, Melbourne, Australia
JAMA Intern Med. 2015;175(10):1721. doi:10.1001/jamainternmed.2015.3824

To the Editor We read with great interest the case series describing occurrence of spontaneous coronary artery dissection (SCAD) in pairs of related individuals from 5 families.1 Familial clustering of such a rare clinical event implies the possibility of genetically determined susceptibility factors in the pathogenesis of SCAD.

We too noticed the phenomenon of a pair of SCAD cases in a mother and daughter treated at our institution.

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